Natural Products as Lead Compounds for Sodium Glucose Cotransporter (SGLT) Inhibitors
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چکیده
منابع مشابه
Natural Products as Lead Compounds for Sodium Glucose Cotransporter (SGLT) Inhibitors.
Glucose homeostasis is maintained by antagonistic hormones such as insulin and glucagon as well as by regulation of glucose absorption, gluconeogenesis, biosynthesis and mobilization of glycogen, glucose consumption in all tissues and glomerular filtration, and reabsorption of glucose in the kidneys. Glucose enters or leaves cells mainly with the help of two membrane integrated transporters bel...
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The mechanism of action of empagliflozin in reducing the risk of adverse cardiovascular outcomes vs placebo in patients with type 2 diabetes mellitus and a high risk of cardiovascular disease in the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Removing Excess Glucose (EMPA-REG OUTCOME) trial is currently unknown. An antiatherosclerotic effect is consider...
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ژورنال
عنوان ژورنال: Planta Medica
سال: 2017
ISSN: 0032-0943,1439-0221
DOI: 10.1055/s-0043-106050